Ferdowsi University of Mashhad
Volume 11 (2019)
Volume 10 (2018)
Volume 9 (2017)
Volume 8 (2016)
Volume 7 (2015)
Volume 6 (2014)
Volume 5 (2013)
Volume 4 (2012)
Volume 3 (2011)
Volume 2 (2010)
Volume 1 (2009)

JCMR METRICS

Link on JCMR

  Publication Start Year 2009
  MSRT Grade (1399/ 2020)  A
  Number of Volumes 12
  Number of Issues 24
  Number of Articles 181
  Number of Submissions 332
  Number of Contributors 542
  Article View 5,571
  Acceptance Rate 55

 

 

WELCOME MESSAGE ...

Dear Colleagues,

As the editor in chief and on behalf of our editorial board, it is a real pleasure to invite you to submit your research manuscripts across all areas of biology to the “Journal of Cell and Molecular Research (JCMR)”. JCMR is a biannually open access on-line scientific journal published in 2009 for the first time.

For any information on how to prepare your manuscript for submission, please check the guidelines on jcmr.um.ac.ir. If you have any further questions, feel free to contact us through jcmr@um.ac.ir or our journal’s managing editor, Ms. Kazemi (Tel: +98 915 699 6326, E-mail: jcmr@um.ac.ir).

Ahmadreza Bahrami

Editor-in-Chief

1. LncRNA HOXD-AS1 Is Upregulated in Ovarian Cancer

Seyedeh Nahid Fotuhi; Mohammad Khalaj-Kondori; Hadis Karimi

Volume 12, Issue 2 , Winter and Spring 2021, Pages 49-55

http://dx.doi.org/10.22067/jcmr.2021.67052.0

Abstract
       Patients with ovarian cancer are mostly diagnosed at advanced stages which leads to poor prognosis and high mortality rate. Deregulation of lncRNA HOXD-AS1 expression associates with cancer development and metastasis. However, the expression level of this lncRNA in ovarian cancer ...  Read More

2. Cloning and Expression of a Fusion Protein Containing Highly Epitopic Regions of Clostridium perfringens Epsilon Toxin and Clostridium novyi Alpha Toxin

Mohsen Mehrvarz; Mohsen Fathi Najafi; Taghi Zahraei Salehi; Behjat Majidi

Volume 12, Issue 2 , Winter and Spring 2021, Pages 56-64

http://dx.doi.org/10.22067/jcmr.2021.68924.1003

Abstract
       Clostridium perfringens and novyi species are two important toxin-producing pathogens which pose a risk to the livestock health. Epsilon and alpha toxins are major toxins of these two pathogens, respectively. Advances in current vaccine industrialization lead to the utilization ...  Read More

3. Signal Transduction of Unique RAS Family Member towards Cell Survival

Saeideh Nakhaei-Rad

Volume 12, Issue 2 , Winter and Spring 2021, Pages 65-73

http://dx.doi.org/10.22067/jcmr.v12i2.2102.1002

Abstract
       Small GTPases of RAS act as central regulators of intracellular signal transduction and translate external stimuli to the various cellular responses. Embryonic stem cell expressed RAS (ERAS) is a member of the RAS family that is specifically expressed in undifferentiated mouse embryonic ...  Read More

4. Immunological Window of Myocardial Infarction

Azadeh Haghighitalab; Mahboubeh Kazemi Noughabi; Shima Minaee; Ahmad Amin; Ahmad Reza Bahrami

Volume 12, Issue 2 , Winter and Spring 2021, Pages 74-86

http://dx.doi.org/10.22067/jcmr.2021.69000.1004

Abstract
       Acute myocardial infarction (MI) describes as an irreversible death of heart muscle which is initiated by a shortage of myocardium oxygen supply and accompanies by a complex of pro- and anti-inflammatory events. During the last decades, innate and adaptive immune responses are considered ...  Read More

5. Comparative in silico Survey of Retinoic Acids as Putative Biomolecules Against VEGF Receptors: A Glycomics-based Approach

Ali Fallah; Esmaeil Samadian; Azadeh Mohammad-Hasani; Abasalt Hosseinzadeh Colagar

Volume 12, Issue 2 , Winter and Spring 2021, Pages 87-96

http://dx.doi.org/10.22067/jcmr.v12i2.89670

Abstract
       In this study, putative interactions between all of the retinoic acid (RA) ligands (all-trans (At), 9-cis (9c), and 13-cis (13c)), and VEGF receptors (VEGFR-1, -2 and -3) were investigated. It was performed considering the glycosylation status of the receptors to achieve a more reliable ...  Read More

6. Identification of Bacterial Proteins in the Gut of Sunn pest, Eurygaster integriceps

Mohammad Saadati; Mahmoud Toorchi

Volume 12, Issue 2 , Winter and Spring 2021, Pages 97-103

http://dx.doi.org/10.22067/jcmr.2021.64305.0

Abstract
       Proteomics is a powerful tool to identify effective proteins in the biochemical reactions of the insect body. Many proteins were reported in the gut lumen and tissues which are essential to complete the physiological role of the alimentary canal of Sunn pest. The gut microbiome of ...  Read More

7. Identification of Suitable Housekeeping Genes for Quantitative Gene Expression Analysis During Retinoic Acid-induced Differentiation of Embryonal Carcinoma NCCIT Cells

Sara Soltanian; Mahboubeh Sheikhbahaei

Volume 12, Issue 2 , Winter and Spring 2021, Pages 104-110

http://dx.doi.org/10.22067/jcmr.v12i2.88457

Abstract
       Real-time quantitative PCR (qRT-PCR) is often used as an effective experimental method for analyzing gene expression. In this method, normalization of target gene expression levels must be performed using housekeeping genes (HKGs). HKGs are used to compensate for difference between ...  Read More

1. Network Analysis of Differential Gene Expression to Identify Hub Genes in Ovarian Cancer

Akram Siavoshi; Mahdieh Taghizadeh; Elahe Dookhe; Mehran Piran; Mahsa Saliani; Shahla Mohammad Ganji

Volume 12, Issue 1 , Summer and Autumn 2020, , Pages 1-9

http://dx.doi.org/10.22067/jcmr.v12i1.85654

Abstract
       Epithelial ovarian cancer (EOC), as a challenging disease among women with poor prognosis and unclear molecular pathogenesis, each year is responsible for 140000 deaths globally. Recent progress in the field revealed the importance of proteins as key players of different biological ...  Read More

2. Cloning and Expression of a Fusion Protein Containing Highly Epitopic Regions of Clostridium perfringens Epsilon Toxin and Clostridium novyi Alpha Toxin

Mohsen Mehrvarz; Mohsen Fathi Najafi; Taghi Zahraei Salehi; Behjat Majidi

Volume 12, Issue 2 , Winter and Spring 2021, , Pages 56-64

http://dx.doi.org/10.22067/jcmr.2021.68924.1003

Abstract
       Clostridium perfringens and novyi species are two important toxin-producing pathogens which pose a risk to the livestock health. Epsilon and alpha toxins are major toxins of these two pathogens, respectively. Advances in current vaccine industrialization lead to the utilization ...  Read More

3. Immunosuppressive Effects of Human Chorionic Gonadotropin (hCG) on Mesenchymal Stromal Cells

Sepideh sadat Hosseini; Shadi Mehrzad; Halimeh Hassanzadeh; Hamid Reza Bidkhori; Mahdi Mirahmadi; Madjid Momeni-Moghaddam; Fatemeh Sadeghifar; Moein Farshchian

Volume 11, Issue 2 , Winter and Spring 2020, , Pages 90-98

http://dx.doi.org/10.22067/jcmr.v11i2.85667

Abstract
       Mesenchymal stem/stromal cells (MSCs) as one of the most important types of adult stem cells secrete a variety of immunomodulatory cytokines. However, their immunomodulatory features strongly depend on the molecular cross-talk between cells and the surrounding microenvironment. Hence, ...  Read More

4. Identification and Functional Profiling of Differentially Expressed Extracellular Vesicle-free MicroRNAs for Efficient Prostate Cancer Diagnosis

Mina Jahandideh; Ebrahim Barzegari

Volume 12, Issue 1 , Summer and Autumn 2020, , Pages 10-21

http://dx.doi.org/10.22067/jcmr.v12i1.87155

Abstract
       MicroRNAs are interesting as cancer diagnostic and prognostic biomarkers because of their unique tissue expression profiles, higher stability in the blood in comparison to mRNAs, and the possibility for reliable quantification. In the case of prostate cancer (PCa), it is currently ...  Read More

5. Association of TOMM40, CHAT and SORL1 Polymorphisms with the Alzheimer’s Disease in the Turkish-speaking Azeri population in Northwest of Iran

Nazanin Mardokh Rohani; Mohammad Khalaj-Kondari; Majid Khodayi-Shahrak; Mahnaz Talebi; Mohammad Ali Hoseinpur Feizi

Volume 12, Issue 1 , Summer and Autumn 2020, , Pages 41-48

http://dx.doi.org/10.22067/jcmr.v12i1.87325

Abstract
       Recent genome-wide association studies have introduced several genetic variants which contribute to the late-onset Alzheimer's disease (LOAD). Polymorphisms of CHAT, TOMM40, and SORL1 genes have been reported to be associated with the LOAD phenotype. This study was endeavored to evaluate ...  Read More

1. Exploring the Anticancer Efficacy of Mixture of Local Probiotics on MDA-MB-231 and MCF-7 Breast Cell Lines

Mohadese Abdoli; Parisa Fathi Rezaei; Kamran Mansouri

Articles in Press, Accepted Manuscript, Available Online from 27 April 2021

http://dx.doi.org/10.22067/jcmr.2021.68651.1001

Abstract
  The aim of this study was to investigate the cytotoxicity of probiotic mixture on breast cancer cell lines. A mixture of local probiotic bacteria was cultured and the supernatant was lyophilized for performing additional experiments. The antioxidant activity, total phenol content (TPC) and fatty acid ...  Read More

2. Bioassay and Molecular Screening of Nitrate Reductase Enzymes in halophilic bacteria

Saeedeh Sibevieh; Ensieh Salehghamari; Mohammad Ali Amoozegar; Mohammad Reza Zolfaghari; Mohammad Soleimani; Zohre Nasrollahzadeh; Sara Eftekhari Yazdi

Articles in Press, Accepted Manuscript, Available Online from 05 May 2021

http://dx.doi.org/10.22067/jcmr.2021.64301.0

Abstract
  With the increased usage of nitrate fertilizers, as it is a stable ion with high solubility in water, its removal is a challenge for human health. Several physicochemical methods have been examined for nitrate removal of water, but nowadays the biological treatment of it from soil and water are widely ...  Read More

3. Royal Jelly Decreases MMP-9 Expression and Induces Apoptosis in Human Bladder Cancer 5637 Cells

Narges Fazili; Zahra-Soheila Soheili; Saeid Malekzadeh-Shafaroudi; Shahram Samiei; Nasrin Moshtaghi; Abouzar Bagheri

Articles in Press, Accepted Manuscript, Available Online from 09 July 2021

http://dx.doi.org/10.22067/jcmr.2021.68523.1000

Abstract
  Royal jelly (RJ) from queen honeybee larva as a traditional medicine agent has a variety of pharmacological benefits. In the present study, the effect of Royal jelly was investigated on the urinary bladder cancer cell line (HTB-9 5637). To determine the cell viability in different concentrations ...  Read More

4. Comparative Analysis of Commercial CCL21 and CCL21/IL1β Recombinant Protein by In Silico Tools

Ahdiyeh Shahtaghi; Ali Alam Shahnabadi; Kamelia Kohannezhad; Neda Amini; Maria Beihaghi

Articles in Press, Accepted Manuscript, Available Online from 22 July 2021

http://dx.doi.org/10.22067/jcmr.2021.69999.1005

Abstract
  One of the newest diagnostic methods and treatment of cancer is to design new drugs. It is now possible to design a drug with desired properties in theory and evaluate its therapeutic effects through bioinformatics tools. Among the studied drugs; those based on cytokine genes, which increase the body's ...  Read More

5. Vitamin C Loaded Albumin Nanoparticles Treatment and Its Effect on Collagen I and III and mir-133 Genes Expression

Hamid Reza Shojania; Madjid Momeni Moghaddam; Seyed Ebrahim Hossini

Articles in Press, Accepted Manuscript, Available Online from 06 August 2021

http://dx.doi.org/10.22067/jcmr.2021.71443.1011

Abstract
  Wound healing is a complex biological process in which many molecules, including microRNA molecules, play an important role in its regulation. It is well established that reducing mir-155 expression can accelerate wound healing. In this study, the effect of using nanoparticle loaded by vitamin C in wound ...  Read More

6. VEGF-C and p53 Gene Expression in the Normal and Neoplastic Mammary Gland of Canines: A Pilot Study

Mohammadreza Nassiri; Azadeh Safarchi; Masoume Vakili-Azghandi; Vinod Gopalan; Mohammad Doosti; Shahrokh Ghovvati; Ahmad Reza Movassaghi

Articles in Press, Accepted Manuscript, Available Online from 14 August 2021

http://dx.doi.org/10.22067/jcmr.2021.71259.1008

Abstract
  p53 is a tumor suppressor protein that plays an essential role in controlling the cell and vascular endothelial growth factor (VEGF) is one of the most strong and specific angiogenic factors. The main objective of this study was to evaluate the impact of p53 and VEGF-C gene expression in the neoplastic ...  Read More

7. Characterization of lytic bacteriophages infecting antibiotic-resistant Escherichia coli strains isolated from urinary tract infections in the north-west of Iran

Raheleh Majdani

Articles in Press, Accepted Manuscript, Available Online from 15 August 2021

http://dx.doi.org/10.22067/jcmr.2021.70313.1006

Abstract
  Urinary tract infection, as one of the most prevalent bacterial infections, affecting millions of people yearly worldwide. Due to control of increasingly antibiotic resistant infections, it is needed to introduce the alternative approaches such as phage therapy. In this study, isolation, purification ...  Read More

8. A Multi-Faceted Approach for Prediction of Genome Safe Harbor Loci in the Chicken Genome

Nima Dehdilani; Mohsen Fathi Najafi; Hesam Dehghani

Articles in Press, Accepted Manuscript, Available Online from 23 August 2021

http://dx.doi.org/10.22067/jcmr.2021.71604.1015

Abstract
  To achieve a reliable and persistent expression over time, the transgene should be precisely integrated into the genome safe harbor (GSH) loci. Little attention has been paid to find the safe harbor loci of the chicken (Gallus gallus domesticus) genome. Identification and characterization of GSH loci ...  Read More

9. Effect of glutamine stability on the long-term culture and line establishment of chicken primordial germ cells

Sara Yousefi taemeh; Jalil Mehrzad; Hesam Dehghani

Articles in Press, Accepted Manuscript, Available Online from 14 September 2021

http://dx.doi.org/10.22067/jcmr.2021.71863.1017

Abstract
  Primordial germ cells (PGCs) are precursors for mature gametes, which transmit genetic information to the next generation. Due to the importance of PGCs in many fields including developmental biology, genome editing, transgenesis, and conservation of avian genetic resources, a lot of research has focused ...  Read More

10. Understanding the Effect of Natural Products on Breast Cancer via P53-MDM 2 Signal Pathway

Zahra Ghavidel; Madjid Momeni Moghaddam; Toktam Hajar; Eisa Kohan

Articles in Press, Accepted Manuscript, Available Online from 14 September 2021

http://dx.doi.org/10.22067/jcmr.2021.71513.1012

Abstract
  The use of medicinal plants in the treatment of diseases has a long history dating back to the human presence on Earth. Cancer, has always been an incurable disease, and among the various cancers, breast cancer is one of the most important causes of death in women and imposes difficult conditions on ...  Read More

11. The Effect of Androgen Deprivation on the Expression of Connexin-43 mRNA in the Heart

Mahnaz Ghowsi; Nazli Khajehnasiri; Sajjad Sisakhtnezhad

Articles in Press, Accepted Manuscript, Available Online from 20 September 2021

http://dx.doi.org/10.22067/jcmr.2021.71395.1010

Abstract
  Connexin-43 (Cx-43) plays axial roles in the propagation of action potentials and contractile coupling in heart. Down-regulation of Cx-43 in heart is associated with arrhythmia, dilated cardiomyopathy and heart failure. To date, no studies have examined the effects of androgen deprivation therapy (ADT)-induced ...  Read More

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