Ferdowsi University of Mashhad
Volume 15 (2023)
Volume 13 (2021)
Volume 12 (2020)
Volume 11 (2019)
Volume 10 (2018)
Volume 9 (2017)
Volume 8 (2016)
Volume 7 (2015)
Volume 6 (2014)
Volume 5 (2013)
Volume 4 (2012)
Volume 3 (2011)
Volume 2 (2010)
Volume 1 (2009)
Investigation of the Role of Encapsulated miR-372 in Chitosan on Induction of Apoptosis in MCF-7 Cancer Cells

Maryam Nouri; Hanieh Jafary; Maryam Ghobeh

Volume 14, Issue 2 , April 2023, Pages 71-77


  In recent years, various efforts have been made to improve the functional potency of cancer drugs. Due to the fact that microRNA in the cell can act as a tumor inhibitor, it can be used as a suitable treatment for most cancers. In this study, chitosan coating is considered a factor that enhances function ...  Read More

5-azacytidine Increases Tanshinone Production in Endophytic Fungi of Salvia abrotanoides (Kar.) Sytsma

Maryam Varasteh-kojourian; Ali Ganjeali; Javad Asili; Saeid Malekzadeh-Shafaroudi; Akram Taleghani

Volume 14, Issue 2 , April 2023, Pages 78-84


  Endophytic fungi are often producing host plant metabolites. Tanshinones are secondary metabolites of the Salvia genus which are also produced by some endophytic fungi. Efficient secondary metabolite production in endophytic fungi drops significantly after sequential subcultures. 5-azacytidine (5-AC) ...  Read More

Optimization of Molecular Sex Identification in Ostrich Based on Multiplex PCR

Jawad Kadhim Sallal Al-Jorani; Mohammadreza Nassiry; Ali Javadmanesh

Volume 14, Issue 2 , April 2023, Pages 85-90


  Today, ostrich breeding has been widely developed in Iran and other countries due to the ability of this animal to produce quality meat, leather, and oil. However, one of the main problems in breeding them is sex determination using aggressive techniques with low accuracy. This study aimed to determine ...  Read More

A Review of Pharmacological and Cell-based Therapies in Spinal Cord Injury

Shiva Amanollahi; Hossein Kazemi Mehrjerdi

Volume 14, Issue 2 , April 2023, Pages 91-100


  Spinal cord injury (SCI) is a severe central nervous system trauma (CNS) that has two primary and secondary phases. The initial phase, which is irreversible, causes nerve tissue destruction and bleeding. Various factors in the second phase together aggravate the primary damage. One of the important factors ...  Read More

The Evaluation of Gene Expression of GPR83, CA1, AWP1, and WTAP in AGS Cells Stimulated by the Helicobacter pylori cagC Gene

Abbas Doosti; Zahra Khoshfetrat

Volume 14, Issue 2 , April 2023, Pages 101-105


                Gastric carcinoma (GC) is the third leading cause of malignancy-related deaths worldwide, and Helicobacter pylori is one of the identified causes of gastric cancer. The Cag pathogenicity island (cagA, cagC, virB2) is one of ...  Read More

Association Study of rs10090154 and rs1691053 With Predisposition to Prostate Adenocarcinoma in the Iranian Population

Roya Dehquan Dehnavi; Seyed Abdolhamid Angaji; Behnaz Beikzadeh; Hengameh Alibeik; Raheleh Roudi; Behzad Narouie

Volume 14, Issue 2 , April 2023, Pages 106-114


  Prostate cancer is the second most prevalent malignancy in men and the fifth leading cause of death worldwide. It is the second most common urinary tract cancer among Iranian men. The aim of this study was to investigate the association between rs10090154, located on the 8q24 locus, and rs1691053 on ...  Read More

Genetic Association Study of Two Variants within RFX6 and SLC22A3 for Their Potential Role in Prostate Cancer Predisposition

Setare Kakavand; Seyed Abdolhamid Angaji; Behnaz Beikzadeh; Raheleh Roudi; Behzad Narouie

Volume 14, Issue 2 , April 2023, Pages 115-121


  Prostate cancer is one of the leading causes of cancer-related deaths among men worldwide. Research has shown that genetic variations can increase an individual's risk of developing this disease. In this study, we investigated the potential role of two genetic variants, one within RFX6 and another within ...  Read More

Investigating the Effect of Dexamethasone on CYP3A4 and Glucocorticoid Receptor by in silico Analysis

Maria Beihaghi; Shima Ghasemi; Mohammad Reza Beihaghi; Nazanin Ataee; Mahsa Zabetian; Hanieh Hadizadeh

Volume 14, Issue 2 , April 2023, Pages 122-128


  Cytochromes are enzymes of the dehydrogenase class with a hemoprotein structure in which the iron in these compounds undergoes oxidation and reduction reactions upon receiving or losing electrons. Quantitatively speaking, CYP3A4 is the most important isoenzyme of cytochrome P450, oxidizing foreign organic ...  Read More