Ferdowsi University of Mashhad
1. VEGF-C and p53 Gene Expression in the Normal and Neoplastic Mammary Gland of Canines: A Pilot Study

Mohammadreza Nassiri; Azadeh Safarchi; Masoume Vakili-Azghandi; Vinod Gopalan; Mohammad Doosti; Shahrokh Ghovvati; Ahmad Reza Movassaghi

Volume 13, Issue 1 , Summer and Autumn 2021, , Pages 10-18


  p53 is a tumor suppressor protein that plays an essential role in controlling the cell and vascular endothelial growth factor (VEGF) is one of the most strong and specific angiogenic factors. The main objective of this study was to evaluate the impact of p53 and VEGF-C gene expression in the neoplastic ...  Read More

2. Exploring the Anticancer Efficacy of Mixture of Local Probiotics on MDA-MB-231 and MCF-7 Breast Cell Lines

Mohadese Abdoli; Parisa Fathi Rezaei; Kamran Mansouri

Volume 13, Issue 1 , Summer and Autumn 2021, , Pages 54-64


  This study aimed to investigate the cytotoxicity of a probiotic mixture on human breast cancer cell lines. To prepare the mixture, local probiotic bacteria were cultured, and the lyophilized supernatant was applied for downstream experiments. The antioxidant activity, total phenol content (TPC), ...  Read More

3. Understanding the Effect of Natural Products on Breast Cancer via P53-MDM 2 Signal Pathway

Zahra Ghavidel; Madjid Momeni Moghaddam; Toktam Hajjar; Eisa Kohan-Baghkheirati

Volume 13, Issue 1 , Summer and Autumn 2021, , Pages 72-80


  The use of medicinal plants in the treatment of diseases has a long history dating back to the presence of humans on earth. Cancer has almost been an incurable disease, and among the various cancers, breast cancer is the most common type of cancer among women and imposes an enormous burden on patients. ...  Read More

4. A Long noncoding RNA, ANCR, is Unregulated in Bladder and Breast Tumor Tissues

Mahshid Malakootian; Youssef Fouani; Parisa Naeli; Fatemeh Mirzadeh Azad; Seyed Amir Mohsen Ziaee; Seyed Javad Mowla

Volume 7, Issue 1 , Summer and Autumn 2015, , Pages 26-31


  Long non-coding RNAs (lncRNAs) have recently found to have important regulatory roles, and their aberrant expressions and functions are directly linked to carcinogenesis. Both urinary bladder and breast tumors are prevalent neoplasms, with high rates of incidence. To identify a potential expression alteration ...  Read More