Ferdowsi University of Mashhad
Volume 15 (2023)
Volume 14 (2022)
Volume 13 (2021)
Volume 12 (2020)
Volume 11 (2019)
Volume 10 (2018)
Volume 9 (2017)
Volume 7 (2015)
Volume 6 (2014)
Volume 5 (2013)
Volume 4 (2012)
Volume 3 (2011)
Volume 2 (2010)
Volume 1 (2009)
Association of Codon 72 of P53 Gene Polymorphism with Chronic Hepatitis C Virus Infection: A Case Control Study

Sina Gerayli; Alireza Pasdar; Sina Rostami; Samaneh Sepahi; Seyed Mousalreza Hoseini; Reza Jahanian; Aida Gholoobi; Zahra Meshkat; Mitra Ahadi

Volume 8, Issue 2 , December 2016, Pages 46-51

https://doi.org/10.22067/jcmr.v8i2.56120

Abstract
  Single nucleotide polymorphism in codon 72 of p53 gene (Arg/Pro) changes p53 protein structure and affects its activities. Hepatitis C virus (HCV) is believed to induce hepatocellular carcinoma and P53 polymorphisms have been associated with human cancers. The aim of this study was to evaluate genetic ...  Read More

Geometric Mean of 5S rRNA and MiR-16 As A Suitable Normalizer In Esophageal Cancer

Samaneh Khazaei; Sedigheh Gharbi; Seyed Javad Mowla

Volume 8, Issue 2 , December 2016, Pages 52-57

https://doi.org/10.22067/jcmr.v8i2.56251

Abstract
  Esophageal squamous cell carcinoma (ESCC) is a deadly cancer with poor prognosis. In this regard, early diagnosis is of vital importance to cure the tumor in its early stages. Novel cancer diagnostic and therapeutic approaches have been recently introduced based on microRNAs (miRNAs). Also, accurate ...  Read More

Protective Effect of Diosgenin against H2O2-Induced Oxidative Stress on H9C2 Cells

Samaneh Jamshidi; Mehrdad Lahouti; Mohammad Taher Boroushaki; Ali Ganjeali; Ahmad Ghorbani; Mehdi Bihamta toosi

Volume 8, Issue 2 , December 2016, Pages 58-64

https://doi.org/10.22067/jcmr.v0i0.36148

Abstract
  Diosgenin is an important compound in pharmaceutical industry. It has various effects such as hypocholesterolemic action or antioxidant activity in HIV infected patients. Biological oxidation pathways are involved in causing or aggravating heart disease. This study investigated the potential protective ...  Read More

Construction of the Recombinant Lentiviral Vector Containing Human GH1 Gene and Its Expression in HEK293T Cells

Zahra Roudbari; Mohammadreza Nassiri; Mojtaba Tahmoorespur; Aliakbar Haddad-Mashadrizeh; Ali Javadmanesh

Volume 8, Issue 2 , December 2016, Pages 71-77

https://doi.org/10.22067/jcmr.v8i2.22857

Abstract
  Human growth hormone (hGH) is a protein with multiple roles in a range of biological functions such as protein, carbohydrates and lipid metabolisms as well as immunity, tissue development and overall growth. One of the major class of biopharmaceuticals in mammalian cells is the production of recombinant ...  Read More

Unravelling Over-Represented Amino Acids in Protein Structure of Allergen Proteins; A Large-Scale Study

Nassim Rahmani; Esmaeil Ebrahimie; Ali Niazi; Najaf Allahyari Fard; Bijan Bambai; Zarrin Minuchehr; Mansour Ebrahimi

Volume 8, Issue 2 , December 2016, Pages 65-70

https://doi.org/10.22067/jcmr.v0i0.60190

Abstract
  Allergens are proteins or glycoproteins which make widespread disorders that can lead to a systemic anaphylactic shock and even death within a short period of time. Understanding the protein features that are involved in allergenicity is important in developing future treatments as well as engineering ...  Read More

Transient Expression of Coat Protein of Foot and Mouth Disease Virus (FMDV) in Alfalfa (Medicago sativa) by Agroinfiltration

Maziar Habibi-Pirkoohi; Saeid Malekzadeh-Shafaroudi; Hasan Marashi; Saeid Zibaee; Afsaneh Mohkami; Saba NejatizaXeh

Volume 8, Issue 2 , December 2016, Pages 83-89

https://doi.org/10.22067/jcmr.v8i2.44884

Abstract
  An Agrobacterium-mediated transient gene expression assay was carried out in alfalfa (Medicago sativa) leaves for expression of a chimeric gene encoding a part of capsid protein of Foot and Mouth Disease virus called VP1. The plant leaves were transformed via agroinfiltration procedure. The presence ...  Read More

Purification and Characterization of an Extracellular Phosphatase Enzyme From Bacillus spp.

Maryam Parhamfar; Arastoo Badoei-Dalfard; Milad Parhamfar; Shohreh Fahimi Rad

Volume 8, Issue 2 , December 2016, Pages 90-97

https://doi.org/10.22067/jcmr.v8i2.58676

Abstract
  Phosphorus is one of the most important nutrients for plant growth and development. Chemical Pi fertilizer is used to provide the phosphorus for the plants, but it is mostly fixed in the soil into insoluble form and become unavailable to the plants. Phosphate-solubilizing bacteria have lots of application ...  Read More