Ferdowsi University of Mashhad
Volume 15 (2023)
Volume 14 (2022)
Volume 13 (2021)
Volume 12 (2020)
Volume 11 (2019)
Volume 10 (2018)
Volume 9 (2017)
Volume 8 (2016)
Volume 7 (2015)
Volume 6 (2014)
Volume 5 (2013)
Volume 4 (2012)
Volume 3 (2011)
Volume 2 (2010)
Volume 1 (2009)
Gene Silencing Method Based on DNA

Mitra Riasi; Elnaz Karbaschian; Ali Javadmanesh

Volume 15, Issue 1 , October 2023, , Pages 7-18

https://doi.org/10.22067/jcmr.2023.84052.1077

Abstract
  DNA-based approaches can now be utilized as low-risk methods to change gene expression. It appears that this approach has the ability to partially replace RNA-based approaches for altering gene expression, which in the majority of cases leads to immunological responses in patients. When utilized as a ...  Read More

Effect of Intramuscular and Intraperitoneal Injections of conjugated MSTN-siRNA-cholesterol on Inhibition of Myostatin Gene expression

Mitra Riasi; Sina Mozaffari Jovin; Ali Javadmanesh

Volume 14, Issue 1 , October 2022, , Pages 20-27

https://doi.org/10.22067/jcmr.2022.77774.1045

Abstract
  Myostatin (MSTN) is primarily expressed in skeletal muscle tissue and acts as a negative regulator of skeletal muscle growth by inhibiting differentiation and proliferation of myoblasts. Inhibition of MSTN expression could result in muscular hypertrophy. An effective therapeutic approach based on specific ...  Read More

MicroRNA-mediated Resistance to Plant Viruses

amir ghaffar shahriari; Aminallah Tahmasebi

Volume 10, Issue 1 , September 2018, , Pages 40-46

https://doi.org/10.22067/jcmr.v10i1.70766

Abstract
  MicroRNAs (miRNAs) are 20-24 nucleotide small RNAs which are processed from nuclear-encoded transcripts. miRNAs control the expression of target transcripts by cleaving or translational inhibition of the target RNAs. Artificial microRNAs (amiRNAs) are modified endogenous miRNA precursors in which the ...  Read More