Molecular Interactions of lncRNAs: Cellular Fate Determination and Tissue Regeneration

Document Type : Editorial

Authors

Monireh Bahrami

Muhammad Irfan-Maqsood

Ferdowsi University of Mashhad

https://doi.org/10.22067/jcmr.v7i2.40861

Abstract

LncRNAs (long non-coding RNAs) are responsible to control the degradation process, RNA stability, orchestration, inhibition, transcription and histone modification etc. These RNAs have been termed as the key agents of several mechanisms such as development, organogenesis and regeneration of damaged tissues etc. They interact with a number of partner molecules either protein, RNAs or DNAs and control the cellular behaviour while differentiation or maintaining the stem cell status. This editorial is discussing the significance of lncRNAs as therapeutic target in stem cell therapy field.

Keywords

LncRNAs

Regeneration

Molecular interactions

Stem cell fate

Differentiation

20.1001.1.20089147.2015.7.2.1.4

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