Ferdowsi University of Mashhad
Volume 15 (2023)
Volume 14 (2022)
Volume 13 (2021)
Volume 12 (2020)
Volume 11 (2019)
Volume 10 (2018)
Volume 9 (2017)
Volume 8 (2016)
Volume 7 (2015)
Volume 6 (2014)
Volume 5 (2013)
Volume 4 (2012)
Volume 3 (2011)
Volume 2 (2010)
Volume 1 (2009)
Investigating the Effect of Dexamethasone on CYP3A4 and Glucocorticoid Receptor by in silico Analysis

Maria Beihaghi; Shima Ghasemi; Mohammad Reza Beihaghi; Nazanin Ataee; Mahsa Zabetian; Hanieh Hadizadeh

Volume 14, Issue 2 , April 2023, , Pages 122-128


  Cytochromes are enzymes of the dehydrogenase class with a hemoprotein structure in which the iron in these compounds undergoes oxidation and reduction reactions upon receiving or losing electrons. Quantitatively speaking, CYP3A4 is the most important isoenzyme of cytochrome P450, oxidizing foreign organic ...  Read More

In silico Study to Identification of Potential SARS-CoV-2 Main Protease Inhibitors: Virtual Drug Screening and Molecular Docking with AutoDock Vina and Molegro Virtual Docker

Mohammad Amin Manavi

Volume 13, Issue 2 , April 2022, , Pages 108-112


  Coronavirus disease 2019 (COVID-19) has emerged in Wuhan, China, and because of fast transmission, it has led to its extensive prevalence in almost all countries, which has made it a global crisis. Drug repurposing is considered a fast way to discover new applications of the current drugs. This study ...  Read More

Molecular docking approach of monoamine oxidase B inhibitors for identifying new potential drugs: Insights into drug-protein interaction discovery

Salimeh Raeisi

Volume 5, Issue 1 , November 2013, , Pages 24-33


  Monoamine oxidase (EC, or amine oxidoreductase catalyzes the oxidative deamination of biogenic amines. Abnormal action of the monoamine oxidase B has been associated with neurological dysfunctions including parkinson´s disorder. Monoamine oxidase B inhibitors divulged that these agents were ...  Read More