Ferdowsi University of Mashhad
1. Signal Transduction of Unique RAS Family Member towards Cell Survival

Saeideh Nakhaei-Rad

Volume 12, Issue 2 , Winter and Spring 2021, , Pages 65-73


       Small GTPases of RAS act as central regulators of intracellular signal transduction and translate external stimuli to the various cellular responses. Embryonic stem cell expressed RAS (ERAS) is a member of the RAS family that is specifically expressed in undifferentiated mouse embryonic ...  Read More

2. Network Analysis of Differential Gene Expression to Identify Hub Genes in Ovarian Cancer

Akram Siavoshi; Mahdieh Taghizadeh; Elahe Dookhe; Mehran Piran; Mahsa Saliani; Shahla Mohammad Ganji

Volume 12, Issue 1 , Summer and Autumn 2020, , Pages 1-9


       Epithelial ovarian cancer (EOC), as a challenging disease among women with poor prognosis and unclear molecular pathogenesis, each year is responsible for 140000 deaths globally. Recent progress in the field revealed the importance of proteins as key players of different biological ...  Read More

3. Non-coding RNAs Could Be New Tools for Cancer Treatment

Atieh Teymoori; Mojtaba Teimoori; Madjid Momeni-Moghaddam

Volume 9, Issue 1 , Summer and Autumn 2017, , Pages 44-53


  For 50 years, the term gene is synonymous with regions of the genome gene that coding by mRNAs and translate to protein. nonetheless, Genome wide Recent studies have revealed that regulating gene expression through degradation or translational inhibition of their point mRNAs and thus attend in a wide ...  Read More

4. Cytotoxic activity of Isatis campylocarpa, an Iranian endemic plant, on human cancer cell lines

Sasan Mohsenzadeh; Leila Najafi; Zahra Amirghofran; Ahmad Reza Khosravi

Volume 1, Issue 1 , Summer and Autumn 2009, , Pages 51-56


  Abstract The antineoplastic activities of alcoholic and aqueous extracts of the roots, stems and leaves of Isatis campylocarpa an endemic species of the Brassicaceae family from Iran, investigated on the growth of Jurkat as an acute lymphocytic leukemia cell line, K562 as a chronic myelogenous leukemia ...  Read More