Ferdowsi University of Mashhad
1. VEGF-C and p53 Gene Expression in the Normal and Neoplastic Mammary Gland of Canines: A Pilot Study

Mohammadreza Nassiri; Azadeh Safarchi; Masoume Vakili-Azghandi; Vinod Gopalan; Mohammad Doosti; Shahrokh Ghovvati; Ahmad Reza Movassaghi

Volume 13, Issue 1 , Summer and Autumn 2021, , Pages 10-18


  p53 is a tumor suppressor protein that plays an essential role in controlling the cell and vascular endothelial growth factor (VEGF) is one of the most strong and specific angiogenic factors. The main objective of this study was to evaluate the impact of p53 and VEGF-C gene expression in the neoplastic ...  Read More

2. Identification of Breast Cancer Associated Putative Functional Single Nucleotide Polymorphisms in the Iranian Population through In Silico Analyses

Vida Nadafi Sichani; Seyed Alireza Emami; Morteza Bitaraf Sani; Mohammadreza Nassiri; Vinod Gopalan

Volume 12, Issue 1 , Summer and Autumn 2020, , Pages 22-32


       Previous studies have found several distinct alleles at both levels of transcriptional activity and protein-DNA binding manners in breast cancer patients vs. healthy individuals through multi-step experimental approaches. This study presents a computational-based model to investigate ...  Read More