Ferdowsi University of Mashhad
1. Identification of Breast Cancer Associated Putative Functional Single Nucleotide Polymorphisms in the Iranian Population through In Silico Analyses

Vida Nadafi Sichani; Seyed Alireza Emami; Morteza Bitaraf Sani; Mohammadreza Nassiri; Vinod Gopalan

Volume 12, Issue 1 , Summer and Autumn 2020, , Pages 22-32


       Previous studies have found several distinct alleles at both levels of transcriptional activity and protein-DNA binding manners in breast cancer patients vs. healthy individuals through multi-step experimental approaches. This study presents a computational-based model to investigate ...  Read More

2. Allelic polymorphism of K-casein, β-Lactoglobulin and leptin genes and their association with milk production traits in Iranian Holstein cattle

Yahya Mohammadi; Ali Asghar Aslaminejad; Mohammad Reza Nassiry; Ali Esmailizadeh Koshkoieh

Volume 5, Issue 2 , Summer and Autumn 2013, , Pages 75-80


  The purpose of this study was to investigate the polymorphism of K-casein (K-CN), β-Lactoglobulin (B-LG) and leptin (LP) genes in Iranian Holstein cattle by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique. DNA was extracted from blood samples of 139 cows using ...  Read More

3. Cloning, nucleotide sequencing and bioinformatics study of NcGRA7, an immunogen from Neospora caninum

Mahdi Soltani; Mohammadreza Nassiri; Alireza Sadrebazzaz; Mojtaba Tahmoorespoor

Volume 5, Issue 1 , Summer and Autumn 2013, , Pages 3-12


  Neospora caninum is an obligate intracellular parasitic protozoa and considered as causal agent of Neosporosis which infect wide variety of hosts. NcGRA7 is an immunodominant antigen recognized by sera from bovines, naturally infected by N. caninum, which is used as a powerful target for recombinant ...  Read More

4. Computational Analyses for Identification Novel MicroRNAs from Cattle and Sheep

Balal Sadeghi; Mohammadreza Nassiri; Ali Masoudi-Nejad; Mojtaba Tahmoorespour; Hesam Dehghani; Hamed Ahmadi

Volume 4, Issue 2 , Winter and Spring 2012, , Pages 62-67


  MicroRNAs (miRNA) are a class of noncoding and regulatory RNA molecules about 22 nucleotides in length. MicroRNAs regulate gene expression by an RNA interfering pathway through cleavage or inhibition of the translation of target mRNA. Many miRNAs have been reported for their important roles in developmental processes ...  Read More

5. Amino acid diversity of antigenic sites of Iranian type O foot-and-mouth disease virus

Abdul-raoof Al-shawkany; Mohammadreza Nassiri; Saied Zibaei; Mojtaba Tahmoorespour; Sayed Mahdi Ziaratnia; Mohsen Fathi Najafi; Alireza Haghparast; Shahrokh Ghovvati; Seyed Hassan Pourseyed; Mohammad Rashtibaf

Volume 3, Issue 2 , Summer and Autumn 2011, , Pages 66-74


  Foot-and-mouth disease (FMD) is a major cause of endemic outbreaks in livestock in Iran. In this study, clinical field samples of foot-and-mouth disease virus were collected from an outbreak in Khorasan Razavi Province during April and August of 2010, and subjected to indirect sandwich ELISA and RT-PCR. ...  Read More