Ferdowsi University of Mashhad
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Investigating the Effect of Dexamethasone on CYP3A4 and Glucocorticoid Receptor by in silico Analysis

Maria Beihaghi; Shima Ghasemi; Mohammad Reza Beihaghi; Nazanin Ataee; Mahsa Zabetian; Hanieh Hadizadeh

Volume 14, Issue 2 , April 2023, , Pages 122-128

https://doi.org/10.22067/jcmr.2023.79707.1060

Abstract
  Cytochromes are enzymes of the dehydrogenase class with a hemoprotein structure in which the iron in these compounds undergoes oxidation and reduction reactions upon receiving or losing electrons. Quantitatively speaking, CYP3A4 is the most important isoenzyme of cytochrome P450, oxidizing foreign organic ...  Read More