Ferdowsi University of Mashhad
Immunological Window of Myocardial Infarction

Azadeh Haghighitalab; Mahboubeh Kazemi Noughabi; Shima Minaee; Ahmad Amin; Ahmad Reza Bahrami

Volume 12, Issue 2 , March 2021, , Pages 74-86


       Acute myocardial infarction (MI) describes as an irreversible death of heart muscle which is initiated by a shortage of myocardium oxygen supply and accompanies by a complex of pro- and anti-inflammatory events. During the last decades, innate and adaptive immune responses are considered ...  Read More

Cost-effective Strategies for Depletion of Endogenous Extracellular Vesicles from Fetal Bovine Serum

Azadeh Haghighitalab; Maryam M. Matin; Fatemeh Khakrah; Ahmad Asoodeh; Ahmad Reza Bahrami

Volume 11, Issue 2 , March 2020, , Pages 42-54


       Despite the prominent therapeutic potentials of stem cells, their use in cell therapy has been challenged with some unreproducible and inconsistent outcomes in addition to the risk of rejection and tumorigenesis. Gaining novel insights to the importance of the conditioned medium, ...  Read More

Supplementary Analysis of Phosphoenolpyruvate Carboxykinase Gene Expression in Developing Seeds of Chickpea

Maria Beihaghi; Ahmad Reza Bahrami; Abdolreza Bagheri; Mohammad Zare Mehrjerdi

Volume 7, Issue 2 , December 2015, , Pages 102-107


  Studies on the genes contributing to the seed filling in chickpea and its protein content might be valuable in engineering plants with seeds of a higher nutritional value. A gene of interest is phosphoenolpyruvate carboxykinase (pepck), encoding a protein with a substantial role in the gluconeogenesis ...  Read More

Designing a SYBR Green Absolute Real time PCR Assay for Specific Detection and Quantification of Bacillus subtilis in Dough Used for Bread Making

Seyed Ali Mortazavi; Ahmad Reza Bahrami; Balal Sadeghi; Maryam Moghaddam Matin

Volume 6, Issue 2 , January 2014, , Pages 83-92


  In present study, a SYBR green based real time PCR assay was developed for specific detection and quantification of Bacillus subtilis in dough used for bread making. New primer pairs were designed to amplify a 212 base pair fragment of the aprE gene. Specificity of these primer pairs was confirmed with ...  Read More

Critical and synergy nodes in insulin-EGF signaling network

Hassan Monhemia; Mohammad Reza Hosseindokht; Mohammareza Bozorgmehr; Ahmad Reza Bahrami

Volume 4, Issue 1 , June 2012, , Pages 18-27


  Signaling pathways are not isolated from their surroundings. They are also intervened by other signaling pathways known as “crosstalk mechanism”. One of the most important crosstalk mechanisms is the insulinEGF network. Although insulin and epidermal growth factor (EGF) networks have some complexity ...  Read More

Design and make up 35S::DREB1A molecular construct to produce environmental stress tolerant plants

Eisa B. Kohan; Mohammad B. Bagherieh-Najjar; Mahnaz Aghdasi; Ahmad Reza Bahrami

Volume 4, Issue 2 , June 2012, , Pages 76-80


  Environmental stresses affect plant growth and cause losses worth hundreds of million dollars of agricultural industry each year. Many genes induced in response to environmental stresses. The DREB1A gene is a stress-inducible transcription factor that its overexpression increased tolerance to environmental ...  Read More

Cytotoxic effect of essential oils from Salvia leriifolia Benth. on human Transitional Cell Carcinoma (TCC) and mouse fibroblast

Samaneh Attaran Dowom; Ahmad Reza Bahrami; Parwaneh Abrishamchi; Morvarid Saeinasab

Volume 3, Issue 2 , August 2011, , Pages 51-56


  Essential oils, with plant origin, have been of special attention in cancer research during recent years. Despite many reports on cytotoxic effects of plants from genus salvia, the potential application of their extracts in cancer therapy remains to be assessed in more precise and detailed examinations ...  Read More

Blastema cells derived from rabbit ear show stem cell characteristics

Maryam Moghaddam Matin; Morvarid Saeinasab; Saeideh Nakhaei-Rad; Mahdi Mirahmadi; Nasser Mahdavi Shahri; Mahmoud Mahmoudi; Ahmad Reza Bahrami

Volume 3, Issue 1 , June 2011, , Pages 25-30


  Abstract Regeneration is a biological phenomenon, which takes place via two main mechanisms: first, dedifferentiation of mature cells followed by their differentiation into functional new cells and second, activation of endogenous somatic stem cells for regeneration of damaged or lost tissues. One ...  Read More

Comparison of pepck gene expression in developing seeds and leaves of chickpea (Cicer arietinum L.) plant

Ahmad Reza Bahrami; Maria Beihaghi; Abdolreza Bagheri; Richard Leegood; Mehdi Ghabooli; Jafar Zolala; Farajollah Shahriari

Volume 1, Issue 2 , July 2009, , Pages 61-67


  Abstract Phosphoenolpyruvate Carboxykinase, encoded by the pepck gene, plays an important role in gluconeogenesis. It also seems to be important in metabolism of nitrogenous compounds in developing seeds of legumes, including amides and ureides which are then transformed into amino acids, necessary ...  Read More